Couple of quick things I've recently come across to do with iTunes:
When you have TotalRecorder installed, you need to tell it only to use its drivers when TR is running, as they appear to conflict with iT giving rise to lovely crackles.
My primary complaint about iTunes for Windows is the space it takes up in the taskbar. This takes care of that quite effectively, even if the buttons are too small (12px by 12px? My display runs at 1280x1024. Think about that for a minute) - you don't really need them.